Professor WAYE Miu Yee, Mary
Professor
- mary-waye@cuhk.edu.hk
- 3943 9302
- BSc, PhD
- ELB624
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Research Interests |
Study of Association of Genetic Variants with Human Conditions, including Psychiatric Disorders |
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Biography
Professor Waye received the degree of Bachelor of Science (Hon) from the University of Western Ontario, Canada, majoring in Bacteriology and Immunology, and then took graduate work and received Ph.D. in Medical Biophysics at the University of Toronto, Canada. During her graduate period, she received support as a research student of the National Cancer Institute. In completing her Ph.D. she received a King George V Fellowship and received her post-doctoral training at the Laboratory of Molecular Biology, Medical Research Council, Cambridge, UK as a National Cancer Institute Research Fellow. She did research in the Division of Protein and Nucleic Acid and later also received training in the Division of Structural Studies in Cambridge. She returned to the University of Toronto as an assistant professor. She has been at The Chinese University of Hong Kong since 1992. She was appointed as the Founding Director of the Croucher Laboratory for Human Genomics in 2004.
Awards & Honours
| Sub Category | Awards & Honour |
|---|---|
| Research Award | Silver Poster Award at Global Proteome Research Congress, Human Proteome Organization (2004) |
| Honour | King George V Fellowship |
| Honour | Top applicant of National Cancer Institute of Canada Research Fellow (1982) |
| Honour | NCI Post-doctoral Fellowship, National Cancer Institute of Canada (1982–1985) |
| Honour | A publication ranked third in LetPub’s in citation ranking for 2015 Medical articles published by Chinese authors (2015年醫學領域中國作者發表的高被引研究論文排行榜排名第三) : Liang, W. C., Fu, W. M., Wong, C. W., Wang, Y., Wang, W. M., Hu, G. X., … Waye, M. M. Y. (2015). The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer. ONCOTARGET, 6(26), 22513-22525. |
External Service
| Sub Category | Awards & Honours |
|---|---|
| Honorary Appointment | Adjunct Professor, School of Biomedical Sciences, The Chinese University of Hong Kong (2014 – 2016) |
| Honorary Appointment | Assistant Professor (cross appointment), Department of Microbiology, Faculty of Medicine, University of Toronto (1991 – 1992) |
| Editorship | Editor in chief, Journal of Biochemistry and Molecular Biology in the Post Genomic Era (2011 – 2014) |
| Editorship | Editor (Chinese translation), Influenza Report 2006 |
| Editorship | Chinese Translator, Supercourse lecture on Myths and Realities of Ebola Virus Disease 2014 |
| Professional Service | Vice-Chairperson, Hong Kong Association of Specific Learning Disabilities (2019 – 2021) |
| Professional Service | Founding President, Hong Kong Society of Behavioural and Neural Genetics (2011 – present) |
| Professional Service | President, Hong Kong Society of Biochemistry and Molecular Biology (2006 – 2018) |
| Professional Service | Member, American Association for the Advancement of Science (1990 – 2014) |
| Professional Service | Member, American Society for Cell Biology (1990 – 2014) |
| Professional Service | Member, Canadian Society of Cell Biologists (1978 – 2014) |
| Professional Service | Lifetime Member, Cell Stress Society International (1999 – present) |
| Professional Service | Member, Hong Kong Association For Specific Learning Disabilities (2003 – present) |
| Professional Service | Member, Hong Kong Society of Medical Genetics (1992 – 2014) |
| Professional Service | Member, Human Genome Organization (1999 – 2014) |
| Professional Service | Member, Human Proteome Organization (2003 – 2014) |
| Professional Service | Member, International Society of Computational Biology (1997 – 2014) |
| Professional Service | Member, Society for the study for Endocrinology, Metabolism and Reproduction, Hong Kong (1992 – 2014) |
| Professional Service | Lifetime Member, Society of Chinese Bioscientists in America (1988 – present) |
| Professional Service | Member, Hong Kong Society of Child Neurology & Developmental Paediatrics (2005 – present) |
| Professional Service | Member of the Grant Panel on Engineering and Science, University of Macau (2011–2016) |
| Professional Service | Member of the Research Programme Sub-committee, Centre for Emerging Infectious Diseases, School of Public Health, Faculty of Medicine, The Chinese University of Hong Kong (2004 – 2006) |
| Professional Service | Judge, Hong Kong Awards for Industry: Technological Achievement, HKSTP (2005 – 2006) |
| Professional Service | Ad hoc Reviewer, Asia-Pacific Psychiatry, Oncogene, Genomics, Genes, BioTechniques, Developmental Medicine & Child Neurology, BMC Medical Genetics, Progress in Neuro-Psychopharmacology and Biological Psychiatry and Experimental Cell Research |
| Professional Service | Ad hoc Reviewer for grant proposal, Wellcome Trust, UK |
| Professional Service | Ad hoc Reviewer for faculty employment/promotion for universities in Singapore, Taiwan, Malaysia and Macau |
Selected Grants
(Selected grants received in recent 5 years in the capacity of PI/Co-I)
| Funding Body | Project Title |
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| Research Institute for Smart Ageing, PolyU | Quantification of brain age by functional MRI data: Complexity and functional connectivity |
| Health Care and Promotion Scheme | New wine in old bottle: The effects of SUDOKU Mind Activation and Revitalizing Training (SMART) Program on cognitive function among people with mild cognitive impairment |
Selected Publications
(10 selected papers published in recent 3 years)
| Publications |
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| Chan, C. W. H., Law, B. M. H., Ng, M. S. N., Wong, C. C. Y., Wong, C. W. Y., Quinley, M., Orgusyan, J. M., Chow, K. M., & Maye, M. M. Y. (2021). Association of single nucleotide polymorphisms of cytochrome P450 enzymes with experience of vasomotor, vaginal and musculoskeletal symptoms among breast cancer patients: A systematic review. BMC Cancer, 21(1), 570. |
| Maggu, A. R., Lau, J. C. Y., Waye, M. M. Y., & Wong, P. C. M. (2021). Combination of absolute pitch and tone language experience enhances lexical tone perception. Sci Rep., 11(1), 1485. |
| Sabit, H., Tombuloglu, H., Rehman, S., Almandil, N. B., Cevik, E., Abdel-Ghany, S., Rashwan, S., Abasiyanik, M.,Waye, M. (2021). Gut microbiota metabolites in autistic children: An epigenetic perspective. Heliyon, 7(1), e06105. |
| Cheung, D. W. S., Koon, J. C. M., Wong, P. H., Yau, K. C., Wat, E. C. L., Chan, J. Y. W., Lau, V. K. M., Ko, E. C. H., Waye, M. M Y., & Fung, K. P. (2021). Combination of atorvastatin or hydrochlorothiazide/amlodipine with Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) for atherosclerosis, hyperlipidaemia, and hypertension: A preclinical in vivo study (abridged secondary publication). Hong Kong Medical Journal, 27 Suppl 2(3), 18–22. |
| Chan, C. W. H., Law, B. M. H., So, W. K. W., Chow, K. M., & Waye, M. M. Y. (2020). Pharmacogenomics of breast cancer: highlighting CYP2D6 and tamoxifen. J Cancer Res Clin Oncol, 146(6), 1395–1404. |
| Chan, H. C., Lau, Y. T., Ding, Q., Li, C. K., Wong, C. M., Shaw, P. C., Waye, M. M. Y., & Tsang, S. Y. (2020). Pinx1t, a novel pinx1 transcript variant, positively regulates cardiogenesis of embryonic stem cells. J Am Heart Assoc, 9(6), e010240. |
| Rao, S., Shi, M., Han, X., Lam, M. H. B., Chien, W. T., Zhou, K. , Liu, G., Wing, Y. K., So, H. C., & Waye, M. M. Y. (2020). Genome-wide copy number variation-, validation- and screening study implicates a new copy number polymorphism associated with suicide attempts in major depressive disorder. Gene, 755, 144901. |
| Chan, C. W. H., Law, B. M. H., Waye, M. M Y., Chan, J. Y. W., So, W. K. W., & Chow, K. M. (2019). Trimethylamine-N-oxide as one hypothetical link for the relationship between intestinal microbiota and cancer – Where we are and where shall we go? J Cancer, 10(23), 5874–5882. |
| Rao, S., Han, X., Shi, M., Siu, C. O., Waye, M. M. Y., Liu, G., & Wing, Y. K. (2019). Associations of the serotonin transporter promoter polymorphism (5-HTTLPR) with bipolar disorder and treatment response: A systematic review and meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry, 89, 214–226. |
| Liang, W. C., Wong, C. W., Liang, P. P., Shi, M., Cao, Y., Rao, S. T., Tsui, S. K. W., Waye, M. M. Y., Zhang, Q., Fu, W. M., & Zhang, J. F. (2019). Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway. Genome Biol., 20(1), 84. |